The 51-year-old singer fears there is no future for the band and he, Larry Mullen Jnr, The Edge and Adam Clayton could part ways in 2012.
He added: “I’m not so sure the future hasn’t dried up. It’s quite likely you might hear from us next year – but it’s equally possible that you won’t.”
The music legends, together since 1976 and worth €327million, are in the recording studio after finishing their record-breaking 360 Tour.
BONO has dropped a bombshell on loyal fans – by suggesting that U2 might call it a day next year.
The legendary rock band is about to re-release their 1991 album Achtung Baby and recently completed the highest-grossing tour of all time.
But frontman Bono, 51, is uncertain about what’s ahead.
He revealed: “I’m not so sure the future hasn’t dried up.
“It’s quite likely you might hear from us next year but it’s equally possible that you won’t. We have so many [new] songs, some of our best.
“But I’m putting some time aside to just go and get lost in the music.
“I want to take my young boys and my wife and just disappear with my iPod Nano and some books and an acoustic guitar.”
He admitted that band mates Larry Mullen, The Edge and Adam Clayton were sick of him questioning whether they had a future in music saying: “The band are like, ‘Will you shut up about being irrelevant?’”
But their frontman hinted that their No Line On The Horizon album might be their last. And it seems Bono isn’t the only one getting cold feet.
The Edge recently admitted that trying to find a new sound led to what he called “a potentially career-ending series of difficulties.”
But there are some who could never imagine a music world without the legendary rockers.
The re-issue of Achtung Baby is a lavish look back at the album that cemented their place in rock history.
But ironically Bono said it was this look back that gave him ideas for the way forward – if U2 decide to carry on. He added: “Being forced to look back at this period reminds me of how we might re-emerge for the next phase.
“And that doesn’t mean that you have to wear some mad welder’s goggles or dress up in women’s clothing. Reinvention is much deeper than that.”